Dopamine and insulin interact in the brain to control junk food cravings. These findings provide evidence that disruptions in this delicate balance make it harder to resist sugary and fatty foods, even when eating them has negative consequences.

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It comes after Heraeus Medical, the main supplier of bone cement to the health service, has had to temporarily halt production at its main site affecting supply for up to two months.

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Shortcuts: For common scenarios, we pre-calculate the travel time/distance (the "shortcut") between border points within the same cluster and also to border points of immediately adjacent clusters.